What is Ketosis? Is it Dangerous?

What is this “ketosis” that you talk about from time to time?

You may see that term on the website, or read about it in various other low-carb plans, and you may even have friends that tell you its going to kill you unless you eat a loaf of bread, pronto! Well, to put it nicely – these people have no idea what the hell they’re talking about. We’re going to break it all down so you’ll know all about this mystical “ketosis” and put the detractors to rest.

Simply putKetosis is the internal metabolic process that burns your excess body fat and uses it for fuel.

That’s right, I bet you didn’t know that those “love handles” we’re actually a super fuel. Shh. Don’t let the grain-lovers at Kashi know, they’ll be putting it in a granola bar before you know it.

Our bodies need glucose to operate, but they don’t care where it comes from – in if we aren’t eating any (like good low-carbers, Aboriginal Tribes, or millions of generations of our Paleolithic descendants), then it needs to come from somewhere. This is were Ketosis comes in – the body can make its own glucose from fat sources (dietary, or in this case body fat).

Basically, It is the (desirable) state your body goes into when you keep your carbohydrate intake low. Since the body doesn’t have any readily available glucose in the bloodstream (aka via dietary sugar), its forced to look elsewhere to get its energy from. It may sound bad, but this is actually quite a good thing (especially if you’ve got a few pounds to lose). The system has to “shift gears” so to say and become an efficient fat-burning machine instead of an inefficient sugar-burning one.

Think about our fat for a minute – in a perfect world – what is the point of it anyways?

Its SUPPOSED to be used kind of like a battery to power the rest of the body, but with modern high-carb diets, no ketosis happens, and that fat can’t be accessed and burned like it was meant to be. To use a well-worn analogy, It would be like constantly charging a battery that you can’t use, since you don’t have the right adapter. Doesn’t really make much sense, now does it?

That’s where ketosis comes in – its the exact opposite of the “fat storing” process.

As always, a little quote from Dr. Michael R. Eades on the matter is always good:

“Fat is the perfect fuel. Part of it provides energy to the liver so that the liver can convert protein to glucose. The unusable part of the fat then converts to ketones, which reduce the need for glucose and sparing the muscle in the process.”

These ‘Ketones’ are the actual fuel that goes to the muscles and the brain (they are by-products of broken down fat cells). In fact its been said that the heart (a muscle) actually prefers ketones to any other fuel and operates more efficiently on it.

Ok, but is it dangerous?

Don’t let anyone tell you that its dangerous – people (and occasionally physicians) get it confused with ketoacidosis. Ketoacidosis is actually an complication of untreated type 1 diabetes, NOT a side-effect of low-carb eating.

I hope that answers most common questions about Ketosis without breaking out the medical jargon (which just confuses people at times – and would have made this post 5x longer). There is a reason I didn’t call the post “A Definitive Guide to Ketosis“.

If I left anything that you’d like clarification on please let me know in the comments, and I’ll update as necessary!

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  • agneshuang
    Hi Ryan. I've been a low-carber for more than a year. A couple weeks ago I decided to get those Ketostix to check if I was in ketosis. I wasn't, even though I was eating virtually no carb except for my veggies, of course. My diet IS pretty high in protein though. Could that be the reason why I was not in ketosis, because my body uses the protein for glucose? If you can clear this up for me I'd appreciate it. Thanks :)
  • Actually, I was just talking to my sister about the testing sticks the other day...

    Just for anyone who doesn't know what we're talking about: Ketostix can be a fun way to try and measure when / if you are in Ketosis, but they aren't perfectly accurate on all people. If you're a data geek like me and you always want to know whats going on "inside there", this is an easy way to try and figure it out. They aren't perfect though - ketostix measure acetoacetic acid in the urine which is a product of discarded ketones that were not used by the various body tissues that thrive on ketones.

    There are several reasons that the sticks might not be indicating ketones for you.

    Remember that we also release ketones through our breath (you know, the funky low-carb acetone breath some people experience) - and depending on how much water you are consuming (we've gotta give the urinary ketones something to ride out in, right!) and your individual biochemistry you'll expell extra ketones one way, the other, or both in varying amounts. So its possible for you to be in heavy ketosis and still not turn the strips purple with urine alone.

    Its also possible that you ARE in ketosis most of the time just not when you happen to test - depending on what you're eating and your particular DNA, the fat-burning cycles could be at any time. Make sure that you're eating a good amount of fat too, that seems to help to switch the body over to fat burning mode (even if its burning dietary fat, its still actively looking for fat to use).

    You said you've been doing it for a year - another would be that the longer you've been on a low-carb (ketogenic) diet, the body gets very good at using ketones for energy - in the beginning they tend to waste them more (i.e. send them out via breath and urine in excessive amounts), but eventually the body gets really good at wringing every last drop of energy out of the ketones in the bloodstream. So theres another ketosis scenario with no noticeable "discharge".

    Lastly, It doesn't take many carbs to stop ketosis in its tracks either - maybe take a good look at the veggies you're eating for any hidden starch monsters - if not, its probably one of the reasons above. :)

    Also, As far as the glucose goes - you'd have to eat a massive excess amount of protein in order to produce enough extra glucose (beyond the brain requirements) to raise your insulin level any measurable amount, so I think you're safe there.

    Thanks for reading and let me know if I can be of any more help!
    (I hope that wasn't too much rambling... hah)
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